Side Effects:

Common Headache, Sleepiness, Insomnia (difficulty in sleeping), Parkinsonism, Akathisia, Dystonia.

Common Abdominal pain, Constipation, Diarrhoea, Epigastric pain, Flatulence, Nausea, Vomiting, Indigestion.

Expert advice for Palip Tablet XR

You can take paliperidone with or without breakfast, however, same pattern to be followed during the entire treatment.
Inform your doctor if you have known cardiovascular disease or family history of QT prolongation and if you are taking medicines that may prolong the QT interval.
Discontinue and inform you doctor immediately if you experience Neuroleptic Malignant Syndrome (NMS), characterised by hyperthermia (fever), muscle rigidity, autonomic instability, altered consciousness, and elevated serum creatine levels.
Inform your doctor if you have a swallowing, stomach or intestinal disorder that reduces your ability to swallow or pass foods by normal bowel movements.
You may suffer from tardive dyskinesia characterized by rhythmical, involuntary movements, predominantly of the tongue and/or face. Inform you doctor if you experience such symptoms.
You may suffer from priapism (prolonged and/or painful erection), inform your doctor if you experience such symptoms.
Do not drive or operate machinery as paliperidone may have some nervous effects and may cause visual disturbances. 
If you are a patient with diabetes, or with schizophrenia, taking paliperidone may increase the risk of developing diabetes. You should monitor glucose regularly while on paliperidone treatment.
Seek immediate medical attention if the thoughts of suicide occur when on paliperidone therapy.
Tell your doctor if you are or planning to become pregnant or are breastfeeding.

Expert advice for Diclofenac
It should be taken with food or milk to avoid getting an upset stomach. It can cause serious complications like stomach bleeding and kidney problems if taken for a long time. Diclofenac can raise a risk of blood clots, heart attack, or a stroke. Inform your doctor if you are pregnant or planning to conceive or breastfeeding. Inform your doctor if you have ever been diagnosed with kidney or liver problems.

Frequently Asked Questions

Q. Is paliperidone the same as risperidone?
Paliperidone gets converted to risperidone in the body and thus exerts similar actions

Q. Is Palip a narcotic?
No, Palip is not a narcotic

Q. Is Palip an atypical antipsychotic?
Yes, Palip is an atypical antipsychotic

Q. How is Palip metabolized?
Palip is metabolized to its active metabolite risperidone by the CYP family of metabolizing enzymes

Q. Does Palip cause weight gain?
Yes, Palip is known to cause weight gain

Q. Does Palip cause erectile dysfunction?
Palip may cause priapism (prolonged and/or painful erection), which may contribute to erectile dysfunction. Please follow your doctor's advice regarding its use

Q. How long does Palip stay in your system?
Oral Palip may take 5 days to clear off from your body/system, whereas the injection may take around 4 to 8 months to clear off from your body/system.

Q. Can Diclofenac be used along with warfarin?
No. Using Diclofenac together with warfarin can increase the risk of serious bleeding from the stomach (Higher than users of either drug alone). Inform your doctor before starting these medications.

Q. Is Diclofenac a painkiller?
Yes. Diclofenac is a pain killer. In fact, it belongs to the class of drugs called non-steroidal anti-inflammatory drugs (NSAIDs). It is commonly used for the treatment of pain in osteoarthritis, rheumatoid arthritis and spondylitis.

Q. Is Diclofenac a narcotic?
No, Diclofenac is not a narcotic. Narcotics are drugs with sleep inducing properties, usual derivatives of Opium like Heroin and Morphine.

Q. Can I use Diclofenac along with vitamins?
Yes, Diclofenac can be taken with vitamins. No drug-drug interactions or any harmful effects have been reported when they are used together.

Q. Can Diclofenac be used for the treatment of hepatitis?
No, Diclofenac is not approved for the treatment of hepatitis. Hepatitis is a condition where the liver is inflamed. Diclofenac can, in fact, cause harm to the liver as a side effect.

Q. Can Diclofenac be used after C-section?
Yes, Diclofenac is a pain killer. C-section is the short name for Cesarean Section which is an operative procedure to deliver the baby through the mother's abdomen and uterus. Diclofenac can be used to treat the pain that may occur after the operation.

Q. Can I take Diclofenac along with misoprostol?
Yes. It can be taken together. Misoprostol protects the stomach from irritating gastric effects of Diclofenac. The combination of medication is used to treat arthritis in patients at high risk of getting stomach/intestinal ulcers and complications from the ulcers (such as bleeding).

Q. Can I take Diclofenac while I am on thyroxine?
Yes, Diclofenac can be taken with thyroxine. No drug-drug interactions or any harmful effects have been reported when they are used together.

Q. Why Diclofenac should be stopped before surgery?
Since Diclofenac has been shown to have blood thinning effects, it can increase the risk of bleeding. Therefore, it is stopped before surgery to prevent excessive loss of blood.

Q. What are the contraindications for Diclofenac?
Diclofenac should not be used if there is an allergic reaction (hypersensitivity) to it, or other pain killers, active ulcer in the stomach, bleeding from the stomach, history of severe heart failure, liver failure, kidney failure and or heart attack.

Q. Can Diclofenac affect the chance of conceiving?
Yes. Diclofenac can sometime cause reversible infertility. Diclofenac by its mechanism of action, may delay or prevent rupture of ovarian follicles, which has been associated with reversible infertility in some women. Consult your doctor before starting this medication.

Q. Why does Diclofenac cause an ulcer?
Diclofenac can cause damage to the lining cells of the stomach by several mechanisms, including the irritant effect on the cells, breaking of the protective barrier properties of lining cells, suppression of prostaglandin production of the stomach, reduction of stomach mucosal blood flow and interference with the repair of superficial injury of the stomach lining.

Q. Why is Diclofenac contraindicated in asthma?
Some patients with asthma are hypersensitive to non-steroidal anti-inflammatory drugs (NSAID) like aspirin which can lead to acute attacks of asthma. Consult your doctor before starting this medication.

Q. Is Diclofenac good for back pain?
Yes, Diclofenac has been found to be effective to reduce back pain. Diclofenac is a pain killer that belongs to the NSAIDs (Non-Steroidal Anti-Inflammatory) class. Other NSAIDs have also been found to be useful in back pain eg. Ibuprofen and Naproxen.

Q. Can I use Diclofenac during my fever treatment?
Yes, Diclofenac can reduce fever. However, commonly used to reduce the pain, particularly that which is seen with Osteoarthritis, Rheumatoid Arthritis and Ankylosing spondylitis.

Q. Can I use Diclofenac to treat a sore throat?
Sore throat is mostly caused by bacteria so antibiotics are given to treat a sore throat whereas Diclofenac is a pain killer so it can be given in cases of throat pain associated with it but only under the prescription of a doctor.

Q. Can I use Diclofenac to treat urinary tract infections (UTI)?
Diclofenac can be used to treat the pain associated with urinary tract infection (UTI) but for complete treatment, a course of antibiotics will be required.

Q. Can Diclofenac cause sedation?
Diclofenac is not known to cause sedation. There have been rare, an isolated case report of sedation with the drug.

Q. Can I take Diclofenac for kidney stones?
Yes,Diclofenac can be used to relieve the pain due to kidney stones. However, there is also a risk of kidney damage with Diclofenac as its side effect. It is advised not to take Diclofenac for a prolonged time for this condition without adequate monitoring.

Q. Can I use Diclofenac for the treatment of arthritis?
Yes, Diclofenac is commonly used for the treatment of pain in osteoarthritis, rheumatoid arthritis, and spondylitis.It belongs to the class of drugs called non-steroidal anti-inflammatory drugs (NSAIDs). .

Q. Can I use Diclofenac with diuretics?
No, Diclofenac should not be used with diuretics. Diclofenac reduces the natriuretic effect of furosemide and thiazides diuretics in some patients. This response has been attributed to inhibition of renal prostaglandin synthesis.

Q. Can I use Diclofenac with mifepristone?
These drugs should not be used together as the effect of mifepristone may be lowered by Diclofenac. Mifepristone is used for medical abortion.

Q. Can I use Diclofenac with lithium?
No.These drugs should not be used together as Diclofenac increases the blood levels of lithium which may further increase the side effects.